To colonize Mars, 21st century scientists seed the planet with algae and cockroaches. 500 years later, the first manned mission to Mars loses contact with Earth, and a second spacecraft is sent to investigate.

Inspired by Sir Arthur Conan Doyle's classic literary characters, the series follows Dr. Wato-san Tachibana and Sara Shelly "Sherlock" Futaba, an eccentric police consultant who uses deduction to solve strange cases in modern-day Japan.

Warrior turned pacifist Kenshin Himura reluctantly takes on a vile assassin scheming to topple the Meiji government with help from some hired killers.