An ex-con, Lance, with ties to the Russian mob and Aryan brotherhood, attempts to live a quiet life after spending fifteen years in prison. His plans for a quiet life are disrupted when members of the Russian mafia recruit him to complete one last assignment to earn his freedom. Lance's last mission goes awry as he finds himself in a bloody retaliation that impacts everyone who crosses his path.

Alice debe ir a Raccoon City para conseguir un antivirus vital, pero el Dr. Isaacs, la Corporación Umbrella y una horda de zombis intentan detenerla.

Presa de la corporación Umbrella, Alice lucha por escapar para poder salvar a la humanidad de un virus que convierte a la gente en zombis.

En un mundo donde los mutantes son discriminados, dos grupos se ven enfrentados, la supremacía de la "Hermandad" y los pacifistas hombres X.