After drunkenly sending a cringeworthy email, hopeless romantic Wes heads to Mexico with her best friends to erase the note before her new love reads it.

The last thing Eddie Mills wants to do is go home and help his dying father, but Eddie flies back. Once there, he has to deal with his crazed family and is forced to confront a past he's been running away from for a long time.

Mad About You centers on the trials and tribulations of a married couple living in New York.