Una fotógrafa es obligada a espiar la infidelidad de un candidato político, convirtiéndose en la única testigo de un delito del que se le acusa falsamente.

Isa, who is aggravated by her life, decides to visit a non traditional doctor. Through the use of hypnotherapy, Isa discovers that her pain is caused by repressed feelings and that the way for her to heal is to say everything she thinks.

A "Diablo Rojo" bus driver, his helper, a priest, and two policemen fall victim to a mysterious spell and end up lost somewhere in the Chiriqui jungle, where they will have to survive the creatures that inhabit the roads, with the old bus as their only refuge.